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Showing 1–4 of 4 results
Advanced filters: Author: Sara Trabanelli Clear advanced filters
  • Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived, but not real, threats.

    • Sara Trabanelli
    • Michel Akselrod
    • Andrea Serino
    ResearchOpen Access
    Nature Neuroscience
    Volume: 28, P: 1968-1977
  • Group 2 innate lymphoid cells (ILC2s) modulate inflammatory and allergic responses, but their function in cancer immunity is still unclear. Here the authors show that, in acute promyelocytic leukaemia, tumour-activated ILC2s secrete IL-13 to induce myeloid-derived suppressor cells and support tumour growth.

    • Sara Trabanelli
    • Mathieu F. Chevalier
    • Camilla Jandus
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14
  • Group 2 innate lymphoid cells (ILC2s) are a component of type 2 immune response recently described to be involved in the regulation of anti-tumor immune responses. Here, the authors show that the expression of the peroxisome proliferator-activated receptor γ (PPAPγ) in human and mouse ILC2 sustains type-2 cytokines secretion and support their pro-tumorigenic role in preclinical cancer models.

    • Giuseppe Ercolano
    • Alejandra Gomez-Cadena
    • Camilla Jandus
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13