The calcium signal is a regulator of the acquisition of a more mesenchymal phenotype. Our work in MDA-MB-468 breast cancer cells identifies a complex relationship between factor-specific induction of the epithelial–mesenchymal marker vimentin and the differential involvement of the canonical store-operated calcium channel ORAI1 and the calcium channel component TRPC1.
- Teneale A. Stewart
- Iman Azimi
- Gregory R. Monteith
