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Showing 1–4 of 4 results

Advanced filters: Author: Sarah Krall Clear advanced filters

Preventing metastatic relapse

Sarah Crunkhorn
Research Highlights30 May 2018
Nature Reviews Drug Discovery

Volume: 17, P: 394
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Genome-wide CRISPR screens in mouse cancer cell lines are used to identify a core, conserved set of genes and pathways that govern how cancer cells evade killing by cytotoxic T lymphocytes.

Keith A. Lawson
Cristovão M. Sousa
Jason Moffat
Research23 Sept 2020
Nature

Volume: 586, P: 120-126
MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity

In leukemia, diverse fusion proteins involving the MLL gene can drive oncogenic activity. Here, the authors describe a dependency of MLL-leukemia cells on the methyltransferase SETD2 to maintain genomic integrity during leukemia initiation and maintenance.

Anna Skucha
Jessica Ebner
Florian Grebien
ResearchOpen Access18 May 2018
Nature Communications

Volume: 9, P: 1-16
Shared endo-phenotypes of default mode dysfunction in attention deficit/hyperactivity disorder and autism spectrum disorder

Julius M. Kernbach
Theodore D. Satterthwaite
Danilo Bzdok
ResearchOpen Access17 Jul 2018
Translational Psychiatry

Volume: 8, P: 1-11