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Showing 1–2 of 2 results
Advanced filters: Author: Sarah Prallet Clear advanced filters

  • HEV-specific antiviral treatment is still lacking. Here, the authors functionally and structurally characterize broadly neutralizing antibodies isolated from HEV convalescent individuals and show that they have protective effects in human liver-chimeric mice infected with HEV.

    • George Ssebyatika
    • Katja Dinkelborg
    • Patrick Behrendt
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • To model hepatocyte function accurately in vitro, it is necessary to generate and maintain a polarized epithelium. Here, the authors describe a protocol to generate polarized human pluripotent stem cell-derived hepatocyte-like cells (HLCs) to model enteric virus production and drug secretion in vitro.

    • Viet Loan Dao Thi
    • Xianfang Wu
    • Charles M. Rice
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13