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Advanced filters: Author: Saravanan Yuvaraj Clear advanced filters
  • Bruton's tyrosine kinase (BTK) is important in B cell receptor (BCR) signalling, and so BTK is altered in many types of B cell-derived malignancy. This Review discusses the molecular biology of BTK, its involvement in the pathogenesis of B cell malignancies and the current efforts to therapeutically target it.

    • Rudi W. Hendriks
    • Saravanan Yuvaraj
    • Laurens P. Kil
    Reviews
    Nature Reviews Cancer
    Volume: 14, P: 219-232