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Showing 1–6 of 6 results
Advanced filters: Author: Sarfaraz Lalani Clear advanced filters

  • The calvarial stem cell niche is populated by a cathepsin K-expressing cell lineage and a newly identified discoidin domain-containing receptor 2-expressing lineage, both of which are required for proper calvarial mineralization.

    • Seoyeon Bok
    • Alisha R. Yallowitz
    • Matthew B. Greenblatt
    Research
    Nature
    Volume: 621, P: 804-812

  • Hedgehog signaling is essential for bone formation. Here, the authors show that the transmembrane protein SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts, suggesting it may be a potential therapeutic target to enhance bone formation.

    • Jun Sun
    • Dong Yeon Shin
    • Matthew B. Greenblatt
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Vertebral osteoblasts in mouse and human are formed from a precursor skeletal stem cell population that is distinct from long bone skeletal stem cells in function, location and transcriptional programme.

    • Jun Sun
    • Lingling Hu
    • Matthew B. Greenblatt
    Research
    Nature
    Volume: 621, P: 602-609

  • Recombinant SLIT3 represents a new mechanistic approach to treating osteoporosis by increasing skeletal CD31hiEMCNhi vascular endothelium.

    • Ren Xu
    • Alisha Yallowitz
    • Matthew B. Greenblatt
    Research
    Nature Medicine
    Volume: 24, P: 823-833