As the indications for T cell immunotherapies, particularly chimeric antigen receptor T cell therapy, continue to expand, a nuanced understanding of their potential adverse effects is required. In this Review, Raddatz and colleagues summarize the mechanisms, epidemiology and management of T cell therapy-associated cytokine release syndrome and subsequent cardiotoxicity.
- Michael A. Raddatz
- Ashley F. Stein-Merlob
- Eric H. Yang
