The protein CPEB, required for learning-related synaptic plasticity in the snail Aplysia, has been suggested to convert from a soluble to a prion-like state. Now these conformational forms of Aplysia CPEB are directly observed, with the prion form showing enhanced binding to target mRNAs.
- Bindu L Raveendra
- Ansgar B Siemer
- Ann E McDermott
