Zhong and colleagues report that zebrafish leakytail (Lkt) promotes ciliogenesis by exporting prostaglandin E2 to upregulate cAMP synthesis. A human orthologue of Lkt, ABCC4, is also important for ciliogenesis in human retinal pigment epithelial cells.
- Daqing Jin
- Terri T. Ni
- Tao P. Zhong