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Showing 1–2 of 2 results
Advanced filters: Author: Sean Treacy-Abarca Clear advanced filters

  • The bacterium Legionella pneumophila, a causative agent of severe pneumonia, replicates inside an endoplasmic reticulum-like organelle in the host cells. Here, Treacy-Abarca and Mukherjee show that the pathogen dampens the host’s unfolded protein response (UPR) pathway by multiple mechanisms.

    • Sean Treacy-Abarca
    • Shaeri Mukherjee
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10

  • Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and to thrive in the inflamed gut.

    • Judith Behnsen
    • Hui Zhi
    • Manuela Raffatellu
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15