Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

Nature

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Cell Death and Differentiation (2)
Cell Death & Disease (1)
Nature Structural & Molecular Biology (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (3)
Comments & Opinion (1)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Cancer
Cell biology
Diseases
Molecular biology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–4 of 4 results

Advanced filters: Author: Sebastian Kehrloesser Clear advanced filters

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

p63 activation in response to DNA damage leads to oocyte death and loss of fertility in women receiving chemotherapy. Activation requires sequential phosphorylation by CHK2 and CK1 kinases, and inhibition of these kinases rescues oocytes from apoptosis induced by chemotherapy.

Marcel Tuppi
Sebastian Kehrloesser
Volker Dötsch
Research26 Feb 2018
Nature Structural & Molecular Biology

Volume: 25, P: 261-269
CHK2 sets the stage for CK1 in oocyte quality control

Sebastian Kehrloesser
Marcel Tuppi
Volker Dötsch
Comments & Opinion17 Apr 2018
Cell Death & Differentiation

Volume: 25, P: 1007-1009
Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree

Christian Osterburg
Marco Ferniani
Volker Dötsch
ResearchOpen Access18 Apr 2023
Cell Death & Disease

Volume: 14, P: 1-18
Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family

Sebastian Kehrloesser
Christian Osterburg
Volker Dötsch
Research22 Jul 2016
Cell Death & Differentiation

Volume: 23, P: 1952-1960

Search

Search articles by subject, keyword or author

Show results from

Advanced search

Quick links

Explore articles by subject
Find a job
Guide to authors
Editorial policies

Nature.com

nature.com sitemap

About Nature Portfolio

About us
Press releases
Press office
Contact us

Discover content

Journals A-Z
Articles by subject
protocols.io
Nature Index

Publishing policies

Nature portfolio policies
Open access

Author & Researcher services

Reprints & permissions
Research data
Language editing
Scientific editing
Nature Masterclasses
Research Solutions

Libraries & institutions

Librarian service & tools
Librarian portal
Open research
Recommend to library

Advertising & partnerships

Advertising
Partnerships & Services
Media kits
Branded content

Professional development

Nature Awards
Nature Careers
Nature Conferences

Regional websites

Nature Africa
Nature China
Nature India
Nature Japan
Nature Middle East

Privacy Policy
Use of cookies
Legal notice
Accessibility statement
Terms & Conditions
Your US state privacy rights

© 2025 Springer Nature Limited