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Showing 1–2 of 2 results
Advanced filters: Author: Sebastian Wabnig Clear advanced filters

  • The GABAergic and peptidergic neuron RIS mediates sleep in Caenorhabditis elegans. The authors demonstrated here that RIS also functions as a locomotion stop neuron. Its optogenetic stimulation caused acute and persistent inhibition of locomotion, and brief intrinsic RIS activity preceded slowing.

    • Wagner Steuer Costa
    • Petrus Van der Auwera
    • Alexander Gottschalk
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • An optogenetic illumination system based on the use of a liquid crystal display projector and video tracking software is reported, which allows real-time multispectral light delivery with high spatial resolution to specified targets in freely moving Caenorhabditis elegans. Also in this issue, Leifer et al. report a similar illumination system using a digital micromirror device. Both methods allow optogenetic perturbation of a variety of neural circuits in the behaving worm.

    • Jeffrey N Stirman
    • Matthew M Crane
    • Hang Lu
    Research
    Nature Methods
    Volume: 8, P: 153-158