MicroRNA-432-5p expression in osteosarcoma cells regulates sprouting and intussusceptive angiogenesis by targeting PDGFB genes. MicroRNA-432-5p/PDGFB signaling can be targeted to treat angiogenesis in osteosarcoma along with other strategies which will further strengthen the effectiveness of antiangiogenic therapy.
- Selvaraj Vimalraj
- Raghunandhakumar Subramanian
- Dhanasekaran Anuradha