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Advanced filters: Author: Semin Erkul Clear advanced filters

  • High mitochondrial DNA content is reported to be beneficial for health. However here, Landoni et al. show that boosting mtDNA replication disrupts cardiac maturation and induces the mitochondrial integrated stress response, ferroptosis and neonatal heart failure.

    • Juan C. Landoni
    • Semin Erkul
    • Anu Suomalainen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11