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Showing 1–3 of 3 results
Advanced filters: Author: Seohyun Byun Clear advanced filters

  • Yeast form part of the host microbiome with known impact on host immunity. Here the authors identify and investigate the impact of commensal yeast-derived polysaccharides in modulating host inflammation, and show its potential for inhibiting inflammation in a number of models of inflammatory diseases.

    • Changhon Lee
    • Ravi Verma
    • Sin-Hyeog Im
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Regulatory T (Treg) cells may lose the expression of their master transcription factor, Foxp3, and be converted to pro-inflammatory cells. Here the authors show that this lineage plasticity may be mediated by the enhanced expression of another transcription regulator, Id2, which suppresses the transcription of Foxp3 to alter Treg lineage stability.

    • Sung-Min Hwang
    • Garima Sharma
    • Sin-Hyeog Im
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13