Nature Search

A virtual memory CD8⁺ T cell-originated subset causes alopecia areata through innate-like cytotoxicity

Virtual memory T cells have antimicrobial functions but whether they can contribute to inflammatory pathology is unclear. Here the authors show that a subset of CD8⁺ T cells that originates from virtual memory T cells upon cytokine stimulation can drive the chronic inflammatory disease alopecia areata via innate-like cytotoxic effector functions.

Joon Seok
Sung-Dong Cho
Su-Hyung Park
Research26 Jun 2023
Nature Immunology

Volume: 24, P: 1308-1317
Hepatocyte KCTD17-mediated SERPINA3 inhibition determines liver fibrosis in metabolic dysfunction-associated steatohepatitis

Yelin Jeong
Ah-Reum Oh
KyeongJin Kim
ResearchOpen Access01 Aug 2025
Experimental & Molecular Medicine

Volume: 57, P: 1673-1685
Significance of bystander T cell activation in microbial infection

T cell receptor–independent triggering of T cells is known as bystander activation. Shin and colleagues review the mechanisms and significance of bystander activation to homeostatic antimicrobial responses and immunopathology.

Hoyoung Lee
Seongju Jeong
Eui-Cheol Shin
Reviews05 Aug 2021
Nature Immunology

Volume: 23, P: 13-22
Study on virtual tooth image generation utilizing CF-fill and Pix2pix for data augmentation

Soo-Yeon Jeong
Eun-Jeong Bae
Sun-Young Ihm
ResearchOpen Access05 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
PD-1 blockade-unresponsive human tumor-infiltrating CD8⁺ T cells are marked by loss of CD28 expression and rescued by IL-15

Kyung Hwan Kim
Hong Kwan Kim
Eui-Cheol Shin
Research24 Apr 2020
Cellular & Molecular Immunology

Volume: 18, P: 385-397

Quick links

Search

Filter By:

A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity

Hepatocyte KCTD17-mediated SERPINA3 inhibition determines liver fibrosis in metabolic dysfunction-associated steatohepatitis

Significance of bystander T cell activation in microbial infection

Study on virtual tooth image generation utilizing CF-fill and Pix2pix for data augmentation

PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15

Search

Quick links

A virtual memory CD8⁺ T cell-originated subset causes alopecia areata through innate-like cytotoxicity

PD-1 blockade-unresponsive human tumor-infiltrating CD8⁺ T cells are marked by loss of CD28 expression and rescued by IL-15