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Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii

Systematic phenotyping of 58,101 mutants of the model eukaryotic alga Chlamydomonas reinhardtii under 121 environmental and chemical stress conditions provides a large resource for characterizing gene function.

Friedrich Fauser
Josep Vilarrasa-Blasi
Robert E. Jinkerson
ResearchOpen Access05 May 2022
Nature Genetics

Volume: 54, P: 705-714
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)

The identification of biomarkers of response to PARP inhibitors can enable selection of appropriate ovarian cancer patients for treatment. In this study, the authors report clinical results and exploratory biomarker analyses from the ARIEL2 phase 2 clinical trial on the safety and efficacy of the PARP inhibitor rucaparib in patients with recurrent ovarian cancers

Elizabeth M. Swisher
Tanya T. Kwan
Iain A. McNeish
ResearchOpen Access03 May 2021
Nature Communications

Volume: 12, P: 1-13
GPR31-dependent dendrite protrusion of intestinal CX3CR1⁺ cells by bacterial metabolites

In the mouse intestine, pyruvate and lactate produced from bacterial metabolites enhance immune responses through inducing dendrite protrusion, mediated by GPR31, of small intestinal mononuclear cells that express CX3CR1.

Naoki Morita
Eiji Umemoto
Kiyoshi Takeda
Research23 Jan 2019
Nature

Volume: 566, P: 110-114
miR-449, identified through antiandrogen exposure, mitigates functional biomarkers associated with ovarian cancer risk

Xia Wang
Ho-Hyung Woo
Setsuko K. Chambers
ResearchOpen Access02 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
Tubal origin of ovarian endometriosis

Zeng Yuan
Lijie Wang
Wenxin Zheng
Research03 Jan 2014
Modern Pathology

Volume: 27, P: 1154-1162
Tubal origin of ‘ovarian’ low-grade serous carcinoma

Jie Li
Nisreen Abushahin
Wenxin Zheng
Research24 Jun 2011
Modern Pathology

Volume: 24, P: 1488-1499

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Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii

Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites

miR-449, identified through antiandrogen exposure, mitigates functional biomarkers associated with ovarian cancer risk

Tubal origin of ovarian endometriosis

Tubal origin of ‘ovarian’ low-grade serous carcinoma

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GPR31-dependent dendrite protrusion of intestinal CX3CR1⁺ cells by bacterial metabolites