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Showing 1–3 of 3 results
Advanced filters: Author: Seungkyu Son Clear advanced filters

  • Yu et al. developed a programmable RNA acetylation system using dCas13–eNAT10 to specifically install N4-acetylcytidine on target RNAs in cells and in vivo, enabling functional studies of RNA acetylation, and revealed the unique role of RNA acetylation in transcript localization.

    • Jihwan Yu
    • Juae Jin
    • Won Do Heo
    Research
    Nature Chemical Biology
    P: 1-14

  • FRET sensors hardly achieve visualization of spatiotemporal dynamics of protein activity in vivo. Here the authors present intensiometric small GTPase biosensors based on dimerization-dependent fluorescent proteins that enable monitoring of activity of small GTPases in the brains of behaving mice at a single spine resolution.

    • Jihoon Kim
    • Sangkyu Lee
    • Won Do Heo
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11