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Advanced filters: Author: Severine Chaumont Clear advanced filters

Cdk5 induces constitutive activation of 5-HT₆ receptors to promote neurite growth

The serotonin receptor 5-HT₆ interacts with a network of proteins that includes Cdk5. Functionally, Cdk5 phosphorylates the receptor at S350 and modulates its activity in inducing neuronal differentiation in a model neuroblastoma cell line and neurite growth in primary neurons.

Fanny Duhr
Paul Déléris
Séverine Chaumont-Dubel
Research01 Jun 2014
Nature Chemical Biology

Volume: 10, P: 590-597
Tracking transmitter-gated P2X cation channel activation in vitro and in vivo

Esther Richler
Severine Chaumont
Baljit S Khakh
Research16 Dec 2007
Nature Methods

Volume: 5, P: 87-93
The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication

The atypical chemokine receptor 3 (ACKR3) is known to regulate cell migration, but the underlying mechanisms are unclear. Here, the authors show, from an interactome analysis, ACKR3 association with the gap junction protein Connexin 43 in vivo and ACKR3-mediated inhibition of astrocyte gap junctional communication.

Amos Fumagalli
Joyce Heuninck
Philippe Marin
ResearchOpen Access25 Sept 2020
Nature Communications

Volume: 11, P: 1-14

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