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Showing 1–2 of 2 results
Advanced filters: Author: Seyda Acar Clear advanced filters

  • During mitosis, kinesin-5 motors are thought to crosslink microtubules in a muscle-like sliding filament mechanism. By combining electron microscopy with other structural tools, the authors reveal how four kinesin-5 polypeptides are organized into bipolar minifilaments.

    • Seyda Acar
    • David B. Carlson
    • Jonathan M. Scholey
    ResearchOpen Access
    Nature Communications
    Volume: 4, P: 1-11

  • Sensory cilia assembly has been proposed to occur through the kinesin-2-driven delivery of precursors to the axoneme tip by intraflagellar transport (IFT). Microscopy analysis and mathematical modelling provide evidence that tubulin subunits are transported to their sites of incorporation into microtubules at axonemal tips by IFT.

    • Limin Hao
    • Melanie Thein
    • Jonathan M. Scholey
    Research
    Nature Cell Biology
    Volume: 13, P: 790-798