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Showing 1–2 of 2 results
Advanced filters: Author: Shaanti Choi-Bose Clear advanced filters

  • The liver is the most common site of metastasis for pancreatic ductal adenocarcinoma (PDAC). Here, the authors demonstrate that β-glucan, a microbial component associated with trained immunity, activates liver-resident macrophages (Kupffer cells) and prevents PDAC metastasis to the liver

    • Stacy K. Thomas
    • Max M. Wattenberg
    • Gregory L. Beatty
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Here the authors show how the liver affects the immune response to pancreatic ductal adenocarcinoma and that cancer immunity and survival outcomes after surgery might be bolstered by therapeutic intervention on hepatocyte release of serum amyloid A proteins.

    • Meredith L. Stone
    • Jesse Lee
    • Gregory L. Beatty
    Research
    Nature Immunology
    Volume: 25, P: 755-763