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Reactome - a knowledgebase of human biological pathways

Bijay Jassal
Esther Schmidt
Lincoln Stein
MultimediaOpen Access03 May 2009
Nature Precedings

P: 1
Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells

Coding variants in peptidylglycine α-amidating monooxygenase (PAM) associated with type 2 diabetes risk negatively impact overall PAM activity via defects in expression and catalytic function, resulting in reduced insulin content and altered dynamics of insulin secretion.

Soren K. Thomsen
Anne Raimondo
Anna L. Gloyn
Research27 Jul 2018
Nature Genetics

Volume: 50, P: 1122-1131
Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase

Marian Raghubir
Syeda M. Azeem
Shahana S. Mahajan
ResearchOpen Access25 Oct 2021
Scientific Reports

Volume: 11, P: 1-13

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Reactome - a knowledgebase of human biological pathways

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells

Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase

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