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Author Correction: The active site of O-GlcNAc transferase imposes constraints on substrate sequence

Shalini Pathak
Jana Alonso
Daan M. F. van Aalten
Amendments and Corrections03 Mar 2023
Nature Structural & Molecular Biology

Volume: 30, P: 564
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells

Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in naïve and effector T cells are identified and it is revealed that the regulation of amino acid transport allows antigen receptors and inflammatory cytokines to repress autophagy flux to shape T cell differentiation.

Linda V. Sinclair
Tom Youdale
Doreen A. Cantrell
ResearchOpen Access27 Feb 2025
Nature Immunology

Volume: 26, P: 429-443
The active site of O-GlcNAc transferase imposes constraints on substrate sequence

O-GlcNAcylation is a post-translational modification catalyzed by O-GlcNAc transferase. Here, a high-throughput activity assay combined with mass spectrometric and crystallographic analyses sheds light on the substrate recognition and specificity of O-GlcNAc transferase.

Shalini Pathak
Jana Alonso
Daan M F van Aalten
Research03 Aug 2015
Nature Structural & Molecular Biology

Volume: 22, P: 744-750
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK

Lindsey A. Allan
Nick Morrice
Paul R. Clarke
Research09 Jun 2003
Nature Cell Biology

Volume: 5, P: 647-654
The genomic landscape of pediatric acute lymphoblastic leukemia

A genomic and transcriptomic analysis of 2,754 childhood acute lymphoblastic leukemias identifies 376 putative driver genes, and associations between disease subtypes and prognosis.

Samuel W. Brady
Kathryn G. Roberts
Charles G. Mullighan
Research01 Sept 2022
Nature Genetics

Volume: 54, P: 1376-1389
Polypharmacy and self-medication among older adults in Indian urban communities—a cross-sectional study

Saibal Das
Pavithra Gnanavel
Cecilia Stålsby Lundborg
ResearchOpen Access03 Feb 2025
Scientific Reports

Volume: 15, P: 1-13
Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

Intracellular proteins are regulated by multiple post-translation modifications. Cantrell and colleagues show that nutrient flux regulates intracellular protein modification by O-GlcNAcylation, which drives thymocyte development and T cell proliferation.

Mahima Swamy
Shalini Pathak
Doreen A Cantrell
Research25 Apr 2016
Nature Immunology

Volume: 17, P: 712-720
Does periodontitis have any association with mild cognitive impairment?

Neeraj Gugnani
Shalini Gugnani
Comments & Opinion09 May 2024
Evidence-Based Dentistry

Volume: 25, P: 83-84

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