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Showing 1–5 of 5 results
Advanced filters: Author: Shangming Tang Clear advanced filters

  • Conditional ablation experiments show that key components of the synaptonemal complex protect double Holliday junction recombination intermediates to ensure their resolution into crossover products, which are required for accurate chromosome segregation during meiosis.

    • Shangming Tang
    • Sara Hariri
    • Neil Hunter
    ResearchOpen Access
    Nature
    P: 1-10

  • Single molecules can generate high-quality single photons for quantum technologies, but coupling to waveguides is difficult. Here, the authors show on-chip background-free resonance fluorescence generation and routing from single molecules with lifetime-limited transition and waveguide-aligned dipoles.

    • Penglong Ren
    • Shangming Wei
    • Xue-Wen Chen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • DNA damage during chromothripsis is caused by deoxyinosine formation on accumulated RNA–DNA hybrids in micronuclei that are then recognized by N-methyl-purine DNA glycosylase and cleaved by apurinic/apyrimidinic endonuclease.

    • Shangming Tang
    • Ema Stokasimov
    • David Pellman
    Research
    Nature
    Volume: 606, P: 930-936

  • Zhiming Cai and colleagues report the exome sequencing of tumor and matched normal tissue from nine transitional cell carcinomas (TCCs) of the bladder, with further screening in 88 additional subjects. The authors identify mutations in chromatin remodeling genes in 59% of the 97 TCC subjects.

    • Yaoting Gui
    • Guangwu Guo
    • Zhiming Cai
    Research
    Nature Genetics
    Volume: 43, P: 875-878