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Showing 1–8 of 8 results
Advanced filters: Author: Shani Perera Clear advanced filters

  • A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.

    • Sam N. Barnett
    • Ana-Maria Cujba
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature Medicine
    Volume: 30, P: 3468-3481

  • A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in fetal and paediatric thymic development.

    • Nadav Yayon
    • Veronika R. Kedlian
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature
    Volume: 635, P: 708-718

  • Single-cell and spatial transcriptomic analysis of eight human heart tissues reveals the cellular profiles and tissue architecture of niches including the cardiac conduction system, and a new tool, drug2cell, identifies drug target expression.

    • Kazumasa Kanemaru
    • James Cranley
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature
    Volume: 619, P: 801-810

  • The study provides a comprehensive transcriptomic atlas of the human gastrointestinal tract across the lifespan, highlighting inflammation-induced changes in epithelial stem cells that alter mucosal architecture and promote further inflammation.

    • Amanda J. Oliver
    • Ni Huang
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature
    Volume: 635, P: 699-707

  • Multi-omics profiling of 45 human lung samples highlights 80 different cell types along the proximal to distal axis of the lung with certain cell types showing enrichment for disease-associated genes. An immune niche for IgA-expressing plasma cells within airway submucosal glands (SMG) is also identified.

    • Elo Madissoon
    • Amanda J. Oliver
    • Kerstin B. Meyer
    ResearchOpen Access
    Nature Genetics
    Volume: 55, P: 66-77

  • The Muscle Aging Cell Atlas presents approximately 200,000 single-cell and single-nuclei transcriptomes from 17 human donors across different ages, uncovering mechanisms of aging in muscle stem cells, myofibers and microenvironment cells, and demonstrates parallels in mouse muscle aging.

    • Veronika R. Kedlian
    • Yaning Wang
    • Hongbo Zhang
    ResearchOpen Access
    Nature Aging
    Volume: 4, P: 727-744