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Showing 1–2 of 2 results
Advanced filters: Author: Sharanjeet Atwal Clear advanced filters

  • Orientia tsutsugamushi (Ot) the causing agent of scrub typhus exits infected cells using a unique mechanism that involves budding off the surface of infected cells. Here, Atwal et al. report that Ots that have budded from their host cells are in a distinct developmental stage than intracellular bacteria and provide the first characterization of this extracellular stage. Both forms are infectious but differ in their physical properties, proteome, and entry mechanism into host cells.

    • Sharanjeet Atwal
    • Jantana Wongsantichon
    • Jeanne Salje
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • The pathogen Orientia tsutsugamushi is an obligate intracellular bacterium that depends on host cell machinery for intracellular movement. Here, Manigrasso et al. provide insights into the molecular mechanisms by which the bacteria hijack the host’s microtubule networks to navigate within cells.

    • Giulia Manigrasso
    • Kittirat Saharat
    • Andrew P. Carter
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16