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Advanced filters: Author: Shari L Caplan Clear advanced filters

Sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress in chemogenetic transgenic mouse lines

Oxidative stress is associated with cardiovascular and neurodegenerative diseases. Here the authors show studies of transgenic chemogenetic mouse lines that develop sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress.

Shambhu Yadav
Markus Waldeck-Weiermair
Thomas Michel
ResearchOpen Access29 May 2023
Nature Communications

Volume: 14, P: 1-14
Small-molecule WNK inhibition regulates cardiovascular and renal function

A selective inhibitor of the With-No-Lysine (K) (WNK) kinase family reduces blood pressure and increases electrolyte excretion in hypertensive rats.

Ken Yamada
Hyi-Man Park
Lauren Monovich
Research05 Sept 2016
Nature Chemical Biology

Volume: 12, P: 896-898

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Sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress in chemogenetic transgenic mouse lines

Small-molecule WNK inhibition regulates cardiovascular and renal function

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