Using quadruple whole-cell recordings, this study tested for synaptic connections among heterogeneous populations of cortical excitatory cells (pyramidal neurons), and found highly connected local circuits of neurons, each reflecting the neurons' long-range projections to a different brain region. The findings illustrate a diversity of dense cortical microcircuitry associated with the variety of information streams that produce our repertoire of behaviours and internal states.
- Solange P. Brown
- Shaul Hestrin