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Showing 1–4 of 4 results
Advanced filters: Author: Shay Laps Clear advanced filters

  • Synthesis of peptides and proteins containing multiple disulfide bonds is challenging, limiting the elucidation of their biological functions. Here, the authors report a general synthetic strategy for fast formation of two and three disulfide bonds in peptides and proteins, and apply it to prepare several therapeutically important peptides.

    • Shay Laps
    • Fatima Atamleh
    • Ashraf Brik
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • The unique properties of selenium have been exploited in protein science. This Review highlights the recent applications of selenium chemistry in protein chemical synthesis, modification, folding, stabilization, the preparation of therapeutic proteins and more.

    • Zhenguang Zhao
    • Shay Laps
    • Norman Metanis
    Reviews
    Nature Reviews Chemistry
    Volume: 8, P: 211-229