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Advanced filters: Author: Shenaz Allyjaun Clear advanced filters

  • Mechanical distortion of DNA structure induces off-target binding and cleavage by SpyCas9 at sites with up to ten mismatches, a potential mechanism that exposes cryptic off-target sites in cells during transcription or replication.

    • Matthew D. Newton
    • Benjamin J. Taylor
    • David S. Rueda
    Research
    Nature Structural & Molecular Biology
    Volume: 26, P: 185-192