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Showing 1–3 of 3 results
Advanced filters: Author: Sheng-Quan Zhang Clear advanced filters

  • Xue-Jun Zhang, Jun Wang and colleagues identify mutations in MVK in disseminated superficial actinic porokeratosis, a disorder characterized by defects in epidermal keratinization. MVK encodes mevalonate kinase, an enzyme involved in the biosynthesis of cholesterol and isoprenoids.

    • Sheng-Quan Zhang
    • Tao Jiang
    • Xue-Jun Zhang
    Research
    Nature Genetics
    Volume: 44, P: 1156-1160

  • Xuejun Zhang and colleagues report results of a genome-wide association study of systemic lupus erythematosus (SLE) in a Chinese Han population. Their work identifies nine new SLE susceptibility loci and reveals overlap in the spectrum of risk alleles shared between Chinese Han and European populations.

    • Jian-Wen Han
    • Hou-Feng Zheng
    • Xue-Jun Zhang
    Research
    Nature Genetics
    Volume: 41, P: 1234-1237

  • Youwen Zhou and Xue-Jun Zhang and colleagues report a genome-wide association study of generalized vitiligo, a common autoimmune disorder characterized by loss of melanocytes and depigmentation. The authors identify two independent associations within the MHC region and one new susceptibility locus on chromosome 6q27, which contains the genes RNASET2, FGFR1OP and CCR6.

    • Cheng Quan
    • Yun-Qing Ren
    • Xue-Jun Zhang
    Research
    Nature Genetics
    Volume: 42, P: 614-618