Nature Search

Hidden pressure-stabilized lead reservoirs in Earth’s mantle

High-pressure Pb-S phases stable in Earth’s lower mantle provide a mechanism for long-term sequestration and episodic remobilization of lead, offering a plausible explanation for the missing lead paradox and silicate Earth isotopic heterogeneity.

Siyu Liu
Meng Guo
Simon A. T. Redfern
ResearchOpen Access18 Feb 2026
Nature Communications

P: 1-7
Time-of-day immunochemotherapy in non-small cell lung cancer: a randomized phase 3 trial

In this randomized phase 3 trial, patients with treatment-naive stage III–IV nonsmall cell lung cancer who received sintilimab or pembrolizumab in combination with chemotherapy early in the day (before 15:00 h) experienced longer progression-free survival compared with those receiving late time-of-day infusions.

Zhe Huang
Liang Zeng
Yongchang Zhang
Research02 Feb 2026
Nature Medicine

P: 1-8
Revealing the reaction mechanisms of Li–O₂ batteries using environmental transmission electron microscopy

In situ characterization of the full reaction pathways of a solid state LiO₂ battery shows the formation of hollow nanostructures as a result of the interplay between lithium ion diffusion, electron transport and oxygen gas evolution at the cathode.

Langli Luo
Bin Liu
Chongmin Wang
Research27 Mar 2017
Nature Nanotechnology

Volume: 12, P: 535-539
PD-1/ PD-L1 bispecific antibody IBI318 combined with lenvatinib in advanced non-small cell lung cancer with acquired resistance to immune checkpoint inhibitors: a phase II trial

IBI318 is a recombinant bispecific IgG1 antibody that targets PD-1 and PD-L1. Here the authors report the results of a phase II trial of IBI318 combined with the receptor tyrosine kinase inhibitor lenvatinib in patients with advanced non-small cell lung cancer with acquired resistance to first-line immune checkpoint inhibitors.

Liang Zeng
Zhaohui Ruan
Yongchang Zhang
ResearchOpen Access15 Dec 2025
Nature Communications

Volume: 17, P: 1-14
Gut microbiome predicts personalized responses to dietary fiber in prediabetes: a randomized, open-label trial

Here, in a large-scale clinical trial, the authors associate gut microbiota composition and metabolic status with effectiveness of dietary fiber intervention in prediabetes, and provide a clinically applicable model to guide microbiome-targeted personalized medicine.

Delei Song
Guangli Feng
Yongde Peng
ResearchOpen Access13 Dec 2025
Nature Communications

Volume: 16, P: 1-14
A prospective comparison of early versus late ¹⁸F-FAPI−04 PET/CT imaging for breast cancer diagnosis

Zonglin Li
Guohong Lin
Shidong Lian
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 15, P: 1-9
Three-dimensional porous carbon composites containing high sulfur nanoparticle content for high-performance lithium–sulfur batteries

Lithium–sulfur batteries have high theoretical capacities but their performance is limited by poor conductivity and low stability. Here, the authors fabricate three-dimensional porous graphitic carbon composites containing sulfur nanoparticles and probe the effect of sulfur content on battery performance.

Guoxing Li
Jinhua Sun
Jianxin Geng
ResearchOpen Access01 Feb 2016
Nature Communications

Volume: 7, P: 1-10
Mapping previously undetected trees reveals overlooked changes in pan-tropical tree cover

Accurate tree cover mapping is vital for fighting climate change and land degradation. This high-resolution study reveals that 17% of pan-tropical tree cover was previously undetected, with over half of recent losses linked to human activities.

Shidong Liu
Jie Zhang
Zheng Niu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
L-shaped association between serum chloride levels with 90-day and 365-day all-cause mortality in critically ill patients with COPD: a retrospective cohort study

Shidong Wang
Dai Li
Weibiao Wang
ResearchOpen Access10 Jul 2024
Scientific Reports

Volume: 14, P: 1-9
Efficient and stable Ruddlesden–Popper perovskite solar cell with tailored interlayer molecular interaction

Two-dimensional perovskite solar cells have been engineered to be robust against moisture, high temperatures and light stress.

Hui Ren
Shidong Yu
Wei Huang
Research13 Jan 2020
Nature Photonics

Volume: 14, P: 154-163
Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives

In this work, the authors identify regulators of actin filament assembly involved in chiral organisation of the actin cytoskeleton in single cells and chiral alignment of cells in groups. This provides insights into how actin-driven chirality underlies tissue and organ asymmetry.

Yee Han Tee
Wei Jia Goh
Alexander D. Bershadsky
ResearchOpen Access11 Feb 2023
Nature Communications

Volume: 14, P: 1-17
Differential vegetation drought adaptability in global karst areas

Yuanhuizi He
Li Wang
Fang Chen
ResearchOpen Access16 Oct 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-11
Endothelial protein C receptor promotes retinal neovascularization through heme catabolism

Pathological retinal neovascularization (RNV) is a major cause of blindness. Here, the authors show that endothelial protein C receptor (EPCR) promotes RNV through carbon monoxide derived from heme catabolism, and blocking EPCR offers therapeutic potential for the treating RNV.

Hongyuan Song
Qing Li
Xiaodong Sun
ResearchOpen Access13 Feb 2025
Nature Communications

Volume: 16, P: 1-14
The dataset of main grain land changes in China over 1985–2020

Shidong Liu
Li Wang
Jie Zhang
ResearchOpen Access24 Dec 2024
Scientific Data

Volume: 11, P: 1-10
Novel formulated alumina-silica hybrid sol for the entire consolidation of waterlogged decayed ivory from Sanxingdui ruin site

Yusong Liu
Qingmeng Xu
Shidong Ji
ResearchOpen Access15 Mar 2024
Heritage Science

Volume: 12, P: 1-11
Tandem Mass Tag labelling quantitative acetylome analysis of differentially modified proteins during mycoparasitism of Clonostachys chloroleuca 67–1

Na Jiang
Binna Lv
Manhong Sun
ResearchOpen Access17 Nov 2021
Scientific Reports

Volume: 11, P: 1-11
MicroRNA-212-3p inhibits the Proliferation and Invasion of Human Hepatocellular Carcinoma Cells by Suppressing CTGF expression

Jian-qing Chen
Yang-liu Ou
Hui Lin
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-10
4A tetrahedron system: a synergistic framework for panvascular intervention empowered by flexible electronics

Lingsen You
Yirong Qu
Junbo Ge
ReviewsOpen Access29 Jan 2026
npj Flexible Electronics

P: 1-21
RBM8A confers oxaliplatin resistance in gastric cancer by maintaining EGFR mRNA stability

Yichun Ma
Ying Xiang
Guifang Xu
Research07 Dec 2025
Oncogene

Volume: 45, P: 339-351
Simulation study on coal and ammonia co-firing in a tangential firing boiler under different ammonia injection methods

Wangping Sun
Qifu Lin
Hansheng Feng
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-20
Enhancement resistance to microbiologically influenced stress corrosion of Cu-bearing steel against Bacillus cereus

Bo Liu
Fangyuan Lu
Xiaogang Li
ResearchOpen Access06 Apr 2024
npj Materials Degradation

Volume: 8, P: 1-14
Network toxicology and molecular docking elucidate the hepatotoxic and carcinogenic mechanisms of potassium sorbate validated by in vitro assays

Yueyue Li
Weiqi Dai
Xuanfu Xu
ResearchOpen Access25 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Persistence of peripheral CD8 + CD28− T cells indicates a favourable outcome and tumour immunity in first-line HER2-positive metastatic breast cancer

Xiaoran Liu
Xiangming Cheng
Huiping Li
ResearchOpen Access22 Mar 2024
British Journal of Cancer

Volume: 130, P: 1599-1608
MicroRNA-520f-3p inhibits proliferation of gastric cancer cells via targeting SOX9 and thereby inactivating Wnt signaling

Jian-qing Chen
Zhi-ping Huang
Liang-kai Hu
ResearchOpen Access10 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Proteomics and phosphoproteomics to study Tuina reverses capsule fibrosis in frozen shoulder: a research report based on rats

Yingjie Qiao
Jianmin Wang
Tiantian Zhang
ResearchOpen Access05 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Sucrose triggers a novel signaling cascade promoting Bacillus subtilis rhizosphere colonization

Tao Tian
Bingbing Sun
Yunrong Chai
ResearchOpen Access26 Mar 2021
The ISME Journal

Volume: 15, P: 2723-2737
Electrochemical behavior of 2205 duplex stainless steel in simulated solution containing high concentration Cl⁻ and saturated CO₂ at different temperatures

Yanpeng Li
Shidong Zhu
Shusen Wang
ResearchOpen Access12 Jul 2022
Scientific Reports

Volume: 12, P: 1-15
Screening and characterisation of proteins interacting with the mitogen-activated protein kinase Crmapk in the fungus Clonostachys chloroleuca

Binna Lv
Lele Fan
Manhong Sun
ResearchOpen Access15 Jun 2022
Scientific Reports

Volume: 12, P: 1-13
Core-shell VO₂@TiO₂ nanorods that combine thermochromic and photocatalytic properties for application as energy-saving smart coatings

Yamei Li
Shidong Ji
Minoru Kanehira
ResearchOpen Access02 Apr 2013
Scientific Reports

Volume: 3, P: 1-13
Downregulation of NUP93 aggravates hypoxia-induced death of cardiomyocytes in vitro through abnormal regulation of gene transcription

Lei Pan
Xiao-wei Song
Jun-bo Ge
Research20 Feb 2023
Acta Pharmacologica Sinica

Volume: 44, P: 969-983

Search

Hidden pressure-stabilized lead reservoirs in Earth’s mantle

Time-of-day immunochemotherapy in non-small cell lung cancer: a randomized phase 3 trial

Revealing the reaction mechanisms of Li–O₂ batteries using environmental transmission electron microscopy

PD-1/ PD-L1 bispecific antibody IBI318 combined with lenvatinib in advanced non-small cell lung cancer with acquired resistance to immune checkpoint inhibitors: a phase II trial

Gut microbiome predicts personalized responses to dietary fiber in prediabetes: a randomized, open-label trial

A prospective comparison of early versus late ¹⁸F-FAPI−04 PET/CT imaging for breast cancer diagnosis

Three-dimensional porous carbon composites containing high sulfur nanoparticle content for high-performance lithium–sulfur batteries

Mapping previously undetected trees reveals overlooked changes in pan-tropical tree cover

L-shaped association between serum chloride levels with 90-day and 365-day all-cause mortality in critically ill patients with COPD: a retrospective cohort study

Efficient and stable Ruddlesden–Popper perovskite solar cell with tailored interlayer molecular interaction

Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives

Differential vegetation drought adaptability in global karst areas

Endothelial protein C receptor promotes retinal neovascularization through heme catabolism

The dataset of main grain land changes in China over 1985–2020

Novel formulated alumina-silica hybrid sol for the entire consolidation of waterlogged decayed ivory from Sanxingdui ruin site

Tandem Mass Tag labelling quantitative acetylome analysis of differentially modified proteins during mycoparasitism of Clonostachys chloroleuca 67–1

MicroRNA-212-3p inhibits the Proliferation and Invasion of Human Hepatocellular Carcinoma Cells by Suppressing CTGF expression

4A tetrahedron system: a synergistic framework for panvascular intervention empowered by flexible electronics

RBM8A confers oxaliplatin resistance in gastric cancer by maintaining EGFR mRNA stability

Simulation study on coal and ammonia co-firing in a tangential firing boiler under different ammonia injection methods

Enhancement resistance to microbiologically influenced stress corrosion of Cu-bearing steel against Bacillus cereus

Network toxicology and molecular docking elucidate the hepatotoxic and carcinogenic mechanisms of potassium sorbate validated by in vitro assays

Persistence of peripheral CD8 + CD28− T cells indicates a favourable outcome and tumour immunity in first-line HER2-positive metastatic breast cancer

MicroRNA-520f-3p inhibits proliferation of gastric cancer cells via targeting SOX9 and thereby inactivating Wnt signaling

Proteomics and phosphoproteomics to study Tuina reverses capsule fibrosis in frozen shoulder: a research report based on rats

Sucrose triggers a novel signaling cascade promoting Bacillus subtilis rhizosphere colonization

Electrochemical behavior of 2205 duplex stainless steel in simulated solution containing high concentration Cl⁻ and saturated CO₂ at different temperatures

Screening and characterisation of proteins interacting with the mitogen-activated protein kinase Crmapk in the fungus Clonostachys chloroleuca

Core-shell VO₂@TiO₂ nanorods that combine thermochromic and photocatalytic properties for application as energy-saving smart coatings

Downregulation of NUP93 aggravates hypoxia-induced death of cardiomyocytes in vitro through abnormal regulation of gene transcription

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