Nature Search

Substrate binding and inhibition of the anion exchanger 1 transporter

Capper et al. uncover how bicarbonate binds to the anion exchanger 1 (AE1), elucidate how drugs inhibit AE1 via distinct mechanisms, and generate a series of AE1 inhibitors using structure-based drug discovery.

Michael J. Capper
Shifan Yang
Daniel Wacker
Research07 Sept 2023
Nature Structural & Molecular Biology

Volume: 30, P: 1495-1504
A self-reactivated PdCu catalyst for aldehyde electro-oxidation with anodic hydrogen production

A low-potential dual-side hydrogen production system is more efficient than water splitting but suffers from stability issues. Here, the authors report a self-reactivating PdCu catalyst that operates stably for 120 h, offering an alternative solution for energy-efficient hydrogen production.

Ming Yang
Yimin Jiang
Yuqin Zou
ResearchOpen Access14 Nov 2024
Nature Communications

Volume: 15, P: 1-11
Molecular basis of human trace amine-associated receptor 1 activation

hTA1 is a drug target for several neuropsychiatric disorders. Using cryo-EM and pharmacological assays, the authors illuminate hTA1’s similarity to neurotransmitter receptors and discover that the antipsychotic asenapine potently activates the receptor.

Gregory Zilberg
Alexandra K. Parpounas
Daniel Wacker
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-14
Subgenome parallel selection is associated with morphotype diversification and convergent crop domestication in Brassica rapa and Brassica oleracea

Xiaowu Wang, Jian Wu, Guusje Bonnema and colleagues report resequencing and subgenome selection analysis of 199 Brassica rapa and 119 Brassica oleracea accessions representing diverse morphotypes. They identify 4 subgenome loci with evidence of parallel selection among subgenomes and 15 subgenome loci with evidence of parallel selection between species.

Feng Cheng
Rifei Sun
Xiaowu Wang
Research15 Aug 2016
Nature Genetics

Volume: 48, P: 1218-1224
Crystal structure of the Frizzled 4 receptor in a ligand-free state

The crystal structure of the Frizzled 4 receptor transmembrane domain is reported to a resolution of 2.4 Å in a ligand-free state.

Shifan Yang
Yiran Wu
Fei Xu
Research22 Aug 2018
Nature

Volume: 560, P: 666-670
Hominin occupation of the Chinese Loess Plateau since about 2.1 million years ago

An Early Pleistocene artefact assemblage from the Chinese Loess Plateau indicates that hominins had left Africa by at least 2.1 million years ago, and occupied the Loess Plateau repeatedly for a long time.

Zhaoyu Zhu
Robin Dennell
Tingping Ouyang
Research11 Jul 2018
Nature

Volume: 559, P: 608-612
Enhanced power conversion efficiency in iridium complex-based terpolymers for polymer solar cells

Zhongyuan Xue
Shifan Wang
Wei Huang
ResearchOpen Access11 Jan 2018
npj Flexible Electronics

Volume: 2, P: 1-7
Author Correction: Application and configuration analysis of electric muck transfer equipment in plateau railway tunnel: a case study in southwest China

Xiaoxu Yang
Yuming Liu
Shifan Pei
Amendments and CorrectionsOpen Access15 Apr 2024
Scientific Reports

Volume: 14, P: 1
Influence of biofertilizer on heavy metal bioremediation and enzyme activities in the soil to revealing the potential for sustainable soil restoration

Mohammed Haroun
Shifan Xie
Xiaoqing Qian
ResearchOpen Access24 Nov 2023
Scientific Reports

Volume: 13, P: 1-13
Application and configuration analysis of electric muck transfer equipment in plateau railway tunnel: a case study in southwest China

Xiaoxu Yang
Yuming Liu
Shifan Pei
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-14
Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis

Xiaoling Zeng
Yuan Liao
Leisheng Zhang
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-15

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Substrate binding and inhibition of the anion exchanger 1 transporter

A self-reactivated PdCu catalyst for aldehyde electro-oxidation with anodic hydrogen production

Molecular basis of human trace amine-associated receptor 1 activation

Subgenome parallel selection is associated with morphotype diversification and convergent crop domestication in Brassica rapa and Brassica oleracea

Crystal structure of the Frizzled 4 receptor in a ligand-free state

Hominin occupation of the Chinese Loess Plateau since about 2.1 million years ago

Enhanced power conversion efficiency in iridium complex-based terpolymers for polymer solar cells

Author Correction: Application and configuration analysis of electric muck transfer equipment in plateau railway tunnel: a case study in southwest China

Influence of biofertilizer on heavy metal bioremediation and enzyme activities in the soil to revealing the potential for sustainable soil restoration

Application and configuration analysis of electric muck transfer equipment in plateau railway tunnel: a case study in southwest China

Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis

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