Nature Search

Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

Shin-ichi Horike
Shutao Cai
Terumi Kohwi-Shigematsu
Research19 Dec 2004
Nature Genetics

Volume: 37, P: 31-40
The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice

Aggravation of liver steatosis shifts the hepatocellular death mode from apoptosis to necroptosis in acute and chronic liver damage. Here the authors report that the transcription factor ATF3 regulates this shift through the induction of RIPK3, a regulator of necroptosis.

Yuka Inaba
Emi Hashiuchi
Hiroshi Inoue
ResearchOpen Access23 Jan 2023
Nature Communications

Volume: 14, P: 1-19
Early parental deprivation during primate infancy has a lifelong impact on gene expression in the male marmoset brain

Haruka Shinohara
Makiko Meguro-Horike
Shin-ichi Horike
ResearchOpen Access03 Jan 2024
Scientific Reports

Volume: 14, P: 1-14
Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation

Kenta Kurayoshi
Yusuke Takase
Atsushi Hirao
ResearchOpen Access29 Sept 2023
Cell Death & Disease

Volume: 14, P: 1-11
A maternal high-fat diet induces fetal origins of NASH-HCC in mice

Takao Takiyama
Toshihiro Sera
Yumi Takiyama
ResearchOpen Access30 Jul 2022
Scientific Reports

Volume: 12, P: 1-24
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2

Tatsunori Nishimura
Asuka Nakata
Noriko Gotoh
ResearchOpen Access07 Dec 2018
Oncogene

Volume: 38, P: 2464-2481
Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b

Bo Zhu
Atsushi Ueda
Tadayuki Akagi
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-14
Androgen-responsive FOXP4 is a target for endometrial carcinoma

This study indicates that the androgen/AR system suppresses the malignant activity of endometrioid carcinoma through the downregulation of FOXP4 which will impact new developments in clinical approaches to elderly health.

Kayo Kayahashi
Mahadi Hasan
Takiko Daikoku
ResearchOpen Access18 Jun 2024
Communications Biology

Volume: 7, P: 1-9
Urinary microRNA biomarkers for detecting the presence of esophageal cancer

Yusuke Okuda
Takaya Shimura
Hiromi Kataoka
ResearchOpen Access20 Apr 2021
Scientific Reports

Volume: 11, P: 1-10
Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system

Takashi Iizuka
Kousho Wakae
Hiroshi Fujiwara
ResearchOpen Access15 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples

Quick and accurate measurements of specific metabolites are critical to diagnose certain pathological conditions, but quantification methods for relatively low molecular-weight metabolites are limited. Here, the water-soluble pillar[6]arene is used to specifically and quantitatively detect 1-methylnicotinamide in crude urinary samples.

Masaya Ueno
Takuya Tomita
Tomoki Ogoshi
ResearchOpen Access07 Dec 2020
Communications Chemistry

Volume: 3, P: 1-10
Cortisol overproduction results from DNA methylation of CYP11B1 in hypercortisolemia

Mitsuhiro Kometani
Takashi Yoneda
Yoshiyu Takeda
ResearchOpen Access11 Sept 2017
Scientific Reports

Volume: 7, P: 1-9
Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma

Masaharu Hazawa
Kie Sakai
Richard W. Wong
ResearchOpen Access10 Dec 2019
Oncogene

Volume: 39, P: 2212-2223

Search

Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice

Early parental deprivation during primate infancy has a lifelong impact on gene expression in the male marmoset brain

Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation

A maternal high-fat diet induces fetal origins of NASH-HCC in mice

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2

Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b

Androgen-responsive FOXP4 is a target for endometrial carcinoma

Urinary microRNA biomarkers for detecting the presence of esophageal cancer

Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system

Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples

Cortisol overproduction results from DNA methylation of CYP11B1 in hypercortisolemia

Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma

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