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Showing 1–2 of 2 results
Advanced filters: Author: Shinichiro Akichika Clear advanced filters

  • E. coli and human tRNAs contain 3-(3-amino-3-carboxypropyl)uridine (acp3U) modification. Here the authors identify E. coli TapT and human DTWD1/2 as tRNA aminocarboxypropyltransferases responsible for acp3U formation. Inhibition of acp3U modification results in genome instability in heat-stressed E. coli and growth defects in human cells.

    • Mayuko Takakura
    • Kensuke Ishiguro
    • Tsutomu Suzuki
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12