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Showing 1–5 of 5 results

Advanced filters: Author: Shino Magaki Clear advanced filters

Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection

Zhang et al. performed a multi-regional multi-omics study, identifying brain-wide mitochondrial and synaptic defects in neurons and glial inflammation as key mechanisms underlying central nervous system impairment in COVID-19, potentially triggering neurodegeneration.

Ting Zhang
Yunfeng Li
Daniel H. Geschwind
Research14 Nov 2024
Nature Aging

Volume: 4, P: 1598-1618
Author Correction: Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Shujing Zhang
Ruowei Zhu
Chao Peng
Amendments and Corrections09 Oct 2023
Nature Neuroscience

Volume: 26, P: 2250
Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Pathological α-synuclein (α-Syn) spreading is critical for the progression of many neurodegenerative diseases. The authors demonstrate that soluble α-Syn post-translational modifications (PTMs) dramatically modulate pathological α-synuclein spreading.

Shujing Zhang
Ruowei Zhu
Chao Peng
Research23 Jan 2023
Nature Neuroscience

Volume: 26, P: 213-225
Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

A deep learning model rapidly identifies locality and counts of cored plaques and cerebral amyloid angiopathy in whole slide images comparably to human experts and without a GPU on a standard workstation.

Daniel R. Wong
Shino D. Magaki
Michael J. Keiser
ResearchOpen Access24 Jun 2023
Communications Biology

Volume: 6, P: 1-9
Charcot–Bouchard aneurysms revisited: clinicopathologic correlations

Shino Magaki
Zesheng Chen
Harry V. Vinters
ResearchOpen Access14 Jun 2021
Modern Pathology

Volume: 34, P: 2109-2121