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Showing 1–3 of 3 results
Advanced filters: Author: Shreeya Agrawal Clear advanced filters

  • A COVID-19 test implemented in an automated microfluidic device and leveraging isothermal RNA amplification followed by T7 transcription and Cas13-mediated cleavage of a quenched fluorophore rapidly detects SARS-CoV-2 RNA in saliva samples.

    • Sita S. Chandrasekaran
    • Shreeya Agrawal
    • Patrick D. Hsu
    Research
    Nature Biomedical Engineering
    Volume: 6, P: 944-956

  • Deploying two unrelated CRISPR nucleases in tandem, with multiplexed CRISPR RNAs and a chemically stabilized activator, creates a simple, one-step assay that can rapidly detect attomolar concentrations of RNA without needing target amplification.

    • Tina Y. Liu
    • Gavin J. Knott
    • Jennifer A. Doudna
    Research
    Nature Chemical Biology
    Volume: 17, P: 982-988