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Showing 1–2 of 2 results
Advanced filters: Author: Shu-Ang Peng Clear advanced filters

  • Microtubule-stabilizing agents (MSAs) promote the polymerization of tubulin and are of great interest as anticancer drugs. Here the authors present the crystal structure of the MSA taccalonolide AJ bound to tubulin and give insights into its mode of action, which might help in the design of novel MSAs.

    • Yuxi Wang
    • Yamei Yu
    • Jinliang Yang
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-8