Enterovirus (EV) 71 can cause of severe hand, foot and mouth disease (HFMD), which may lead to fatal pulmonary edema. The authors determined that mast cells contribute to pulmonary edema during EV71 infection and that specific inhibitors of mast cell degranulation may be beneficial as therapy to treat EV71 infection-induced severe HFMD.
- Yuefei Jin
- Chao Zhang
- Guangcai Duan
