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3,4-Dihydroxyphenylacetaldehyde synthase evolved an ordered structure to deliver oxygen to pyridoxal 5’-phosphate for cuticle assembly in the mosquito Aedes aegypti

This study investigates the role of 3,4-dihydroxyphenylacetaldehyde synthase (DHPAAS) in mosquito cuticle formation, a key factor in their development and survival. The findings reveal that DHPAAS is essential for abdominal integrity and egg development, with unique structural features suggesting a novel oxygen delivery mechanism.

Jing Chen
Christopher J. Vavricka
Qian Han
ResearchOpen Access14 May 2025
Nature Communications

Volume: 16, P: 1-13
Protective effects of indole-3-propionic acid against TCP-induced hearing loss in mice by mitigating oxidative stress and promoting neutrophil recruitment

Shuangshuang Mao
Zirui Zhang
Rong Chen
ResearchOpen Access19 Mar 2025
Scientific Reports

Volume: 15, P: 1-15
Non-discriminating engineered masking of immuno-evasive ligands on tumour-derived extracellular vesicles enhances tumour vaccination outcomes

Nano-masking of the surface of tumour-derived extracellular vesicles blocks their immune-evasive action. This improves their phagocytosis by dendritic cells, leading to maturation of T-cell action and culminating in undampened anti-tumour immunity.

Xianguang Ding
JingJing Zhang
Lianhui Wang
Research26 Sept 2024
Nature Nanotechnology

Volume: 20, P: 156-166
A scalable high-porosity wood for sound absorption and thermal insulation

Materials popular for insulation and noise reduction are typically derived from petroleum or minerals or have other environmental costs. This study reports a scalable material for thermal insulation and noise reduction derived from treated wood.

Xinpeng Zhao
Yu Liu
Liangbing Hu
Research09 Jan 2023
Nature Sustainability

Volume: 6, P: 306-315
Research on blasting mechanism and blasting effect of aqueous media in open pit coal mines

Xiaohua Ding
Xin Liu
Chun Zhu
ResearchOpen Access06 Nov 2023
Scientific Reports

Volume: 13, P: 1-17
ERO1L promotes IL6/sIL6R signaling and regulates MUC16 expression to promote CA125 secretion and the metastasis of lung cancer cells

Yuanyuan lei
Ruochuan Zang
Jie He
ResearchOpen Access14 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-15
The membrane-bound and soluble form of melanotransferrin function independently in the diagnosis and targeted therapy of lung cancer

Yuanyuan Lei
Zhiliang Lu
Jie He
ResearchOpen Access30 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-15
TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model

Jiaqi Liu
Nan Wu
Guixing Qiu
Research14 Jan 2019
Genetics in Medicine

Volume: 21, P: 1548-1558
Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance

Yun Che
Jingnan Wang
Jie He
ResearchOpen Access09 Jul 2018
Cell Death & Disease

Volume: 9, P: 1-13
Genome-wide association study of 29 morphological traits in Aegilops tauschii

Yaxi Liu
Lang Wang
Youliang Zheng
ResearchOpen Access27 Oct 2015
Scientific Reports

Volume: 5, P: 1-12
High-effective approach from amino acid esters to chiral amino alcohols over Cu/ZnO/Al₂O₃ catalyst and its catalytic reaction mechanism

Shuangshuang Zhang
Jun Yu
Guanzhong Lu
ResearchOpen Access13 Sept 2016
Scientific Reports

Volume: 6, P: 1-15

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3,4-Dihydroxyphenylacetaldehyde synthase evolved an ordered structure to deliver oxygen to pyridoxal 5’-phosphate for cuticle assembly in the mosquito Aedes aegypti

Protective effects of indole-3-propionic acid against TCP-induced hearing loss in mice by mitigating oxidative stress and promoting neutrophil recruitment

Non-discriminating engineered masking of immuno-evasive ligands on tumour-derived extracellular vesicles enhances tumour vaccination outcomes

A scalable high-porosity wood for sound absorption and thermal insulation

Research on blasting mechanism and blasting effect of aqueous media in open pit coal mines

ERO1L promotes IL6/sIL6R signaling and regulates MUC16 expression to promote CA125 secretion and the metastasis of lung cancer cells

The membrane-bound and soluble form of melanotransferrin function independently in the diagnosis and targeted therapy of lung cancer

TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model

Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance

Genome-wide association study of 29 morphological traits in Aegilops tauschii

High-effective approach from amino acid esters to chiral amino alcohols over Cu/ZnO/Al₂O₃ catalyst and its catalytic reaction mechanism

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