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Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

GWAS in difficult-to-recruit populations identifies variants associated with Lassa fever outcome and susceptibility at loci proximal to LIF, GRM7 and LARGE1.

Dylan Kotliar
Siddharth Raju
Pardis C. Sabeti
ResearchOpen Access07 Feb 2024
Nature Microbiology

Volume: 9, P: 751-762
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

T_reg cells are essential for immune homeostasis, but the transcription factors controlling their cellular identity are incompletely understood. Schumann and colleagues use pooled and arrayed CRISPR screens and scRNA-seq to describe key gene networks in human T_reg cells.

Kathrin Schumann
Siddharth S. Raju
Alexander Marson
Research28 Sept 2020
Nature Immunology

Volume: 21, P: 1456-1466
A miniaturized multi-clamp CMOS amplifier for intracellular neural recording

An integrated circuit amplifier, which is fabricated in a commercial complementary metal–oxide–semiconductor (CMOS) process, can record both voltages and currents with performance that exceeds commercial benchtop instrumentation.

Siddharth Shekar
Krishna Jayant
Kenneth L. Shepard
Research15 Aug 2019
Nature Electronics

Volume: 2, P: 343-350
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Single-cell analysis of lung, heart, kidney and liver autopsy samples shows the molecular and cellular changes and immune response resulting from severe COVID-19 infection.

Toni M. Delorey
Carly G. K. Ziegler
Aviv Regev
Research29 Apr 2021
Nature

Volume: 595, P: 107-113
Effect of heterologous intranasal iNCOVACC^® vaccination as a booster to two-dose intramuscular Covid-19 vaccination series: a randomized phase 3 clinical trial

Venkateshwar et al., explored the effect of Heterologous intranasal iNCOVACC® vaccination as a booster to two-dose intramuscular Covid-19 vaccinations (either by Covishield or Covaxin) in a controlled, randomised, open-label phase 3 clinical trial. This study also aimed to compare these results with homologous booster vaccinations by Covishield or Covaxin.

Venkateshwar Rao Akula
Amit Suresh Bhate
Sai. D Prasad
ResearchOpen Access23 Apr 2025
Communications Medicine

Volume: 5, P: 1-12
Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin^®)

Chandramani Singh
Savita Verma
Krishna Mohan Vadrevu
ResearchOpen Access18 Aug 2023
npj Vaccines

Volume: 8, P: 1-9
Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants

Krishna Mohan Vadrevu
Brunda Ganneru
Krishna Ella
ResearchOpen Access14 Jul 2022
Scientific Reports

Volume: 12, P: 1-13

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Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

A miniaturized multi-clamp CMOS amplifier for intracellular neural recording

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Effect of heterologous intranasal iNCOVACC® vaccination as a booster to two-dose intramuscular Covid-19 vaccination series: a randomized phase 3 clinical trial

Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin®)

Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants

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Effect of heterologous intranasal iNCOVACC^® vaccination as a booster to two-dose intramuscular Covid-19 vaccination series: a randomized phase 3 clinical trial

Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin^®)