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Showing 1–4 of 4 results
Advanced filters: Author: Sidhartha Goyal Clear advanced filters

  • Many experiments have probed the mechanisms by which transplanted stem cells give rise to all the cell types of the blood, but it emerges that the process is different in unperturbed conditions. See Letter p.542

    • Sidhartha Goyal
    • Peter W. Zandstra
    News & Views
    Nature
    Volume: 518, P: 488-490

  • Quach and Farrell et al. report single-cell transcriptomic analysis of over 150,000 cell from 19 human fetal lung tissues and describe the temporal and spatial dynamics of epithelial lineage development. These epithelial lineage trajectories were further identified in human pluripotent stem cell-based models of lung cell differentiation.

    • Henry Quach
    • Spencer Farrell
    • Amy P. Wong
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-24

  • Morphogenesis of tissue sheets is well studied, but mechanisms that shape bulk tissues are unclear. Here, the authors show that mesenchymal cells intercalate in 3D to shape the mouse branchial arch, with cortical forces driving intercalations in a Wnt5a-, Yap/Taz- and Piezo1-dependent manner.

    • Hirotaka Tao
    • Min Zhu
    • Sevan Hopyan
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-18