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Showing 1–3 of 3 results
Advanced filters: Author: Sigrid Noreng Clear advanced filters

  • The EMDataResource Ligand Model Challenge aimed at assessing the reliability and reproducibility of modeling ligands bound to protein and protein–nucleic acid complexes in cryo-EM maps determined at near-atomic resolution. This analysis presents the results and recommends best practices for assessing cryo-EM structures of liganded macromolecules.

    • Catherine L. Lawson
    • Andriy Kryshtafovych
    • Wah Chiu
    Research
    Nature Methods
    Volume: 21, P: 1340-1348

  • NADPH oxidase NOX2 produces superoxide, a reactive oxygen species essential in innate immunity. Here, the authors reveal the structure of the NOX2 core, rationalize disease-causing mutations, and suggest avenues for selective NOX2 pharmacological modulation.

    • Sigrid Noreng
    • Naruhisa Ota
    • James T. Koerber
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11