Nature Search

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

A deep mutational scanning approach identifies mutations that allow subvariants of the prevalent JN.1 SARS-CoV-2 strain to evade Omicron-induced neutralizing antibodies, indicating a need for careful monitoring of this lineage in vaccine development.

Fanchong Jian
Jing Wang
Yunlong Cao
ResearchOpen Access07 Nov 2024
Nature

Volume: 637, P: 921-929
Ammonia mitigation campaign with smallholder farmers improves air quality while ensuring high cereal production

China is the global hotspot of ammonia emissions from croplands, with adverse impacts on human health and the environment. Reporting on a large-scale ammonia reduction trial at the county level in the North Plain China, this study shows that coordinated actions among smallholders can ensure high yields and improved air quality.

Jiahui Kang
Jingxia Wang
Wen Xu
Research31 Aug 2023
Nature Food

Volume: 4, P: 751-761
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Convergent mutations in hotspots of the SARS-CoV-2 Omicron receptor-binding domain can cause immune evasion and maintain sufficient ACE2-binding capability.

Yunlong Cao
Fanchong Jian
Xiaoliang Sunney Xie
ResearchOpen Access19 Dec 2022
Nature

Volume: 614, P: 521-529
Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Exposure to early variants of SARS-CoV-2 results in immune imprinting in mouse models and in humans, reducing neutralizing antibody titres against Omicron variants, which could be mitigated with multiple updated boosters.

Ayijiang Yisimayi
Weiliang Song
Yunlong Cao
ResearchOpen Access22 Nov 2023
Nature

Volume: 625, P: 148-156
Room-temperature direct synthesis of semi-conductive PbS nanocrystal inks for optoelectronic applications

Providing large-scale iodide capped semi-conductive PbS nanocrystals inks preparation for high-throughput manufacturing remains a challenge. Here, the authors propose a direct one step and scalable synthesis method enabling cost reduction and promoting its commercial viability for solar cells.

Yongjie Wang
Zeke Liu
Wanli Ma
ResearchOpen Access13 Nov 2019
Nature Communications

Volume: 10, P: 1-8
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

Biochemical and structural studies of the interactions between antibodies and spike proteins from SARS-CoV-2 Omicron subvariants indicate how these variants have evolved to escape antibody-mediated neutralization.

Yunlong Cao
Ayijiang Yisimayi
Xiaoliang Sunney Xie
ResearchOpen Access17 Jun 2022
Nature

Volume: 608, P: 593-602
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis

CRISPR-mediated gene knockout and activation are used to identify molecules in cancer cells and macrophages that regulate antibody-dependent cancer cell phagocytosis.

Roarke A. Kamber
Yoko Nishiga
Michael C. Bassik
Research08 Sept 2021
Nature

Volume: 597, P: 549-554
Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia/re-oxygenation-induced endothelial autophagy in vitro

Yue Lu
Sijie Wang
Liangqing Zhang
ResearchOpen Access13 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-14
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a

Chengcai Lai
Lihui Liu
Penghui Yang
Research14 May 2021
Cell Death & Differentiation

Volume: 28, P: 2900-2915
STEM enables mapping of single-cell and spatial transcriptomics data with transfer learning

STEM is a transfer-learning-based method that integrates spatial transcriptomics and scRNA-seq data to reconstruct localization at the single-cell level and reveal gene expression variation within cell types in tissues.

Minsheng Hao
Erpai Luo
Xuegong Zhang
ResearchOpen Access06 Jan 2024
Communications Biology

Volume: 7, P: 1-15
Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis

Mingsen Li
Liqiong Zhu
Hong Ouyang
ResearchOpen Access08 Jan 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-11
D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration

Bowen Wang
Li Wang
Hong Ouyang
ResearchOpen Access04 Mar 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-12
Genome assembly of Nannochloropsis oceanica provides evidence of host nucleus overthrow by the symbiont nucleus during speciation

Li Guo et al. assemble the genome of Nannochloropsis oceanica, finding evidence that during the secondary endosymbiosis event responsible for its speciation, its host nucleus was overthrown by a symbiont nucleus. They suggest that the symbiont nucleus became dominant over the host nucleus.

Li Guo
Sijie Liang
Guanpin Yang
ResearchOpen Access03 Jul 2019
Communications Biology

Volume: 2, P: 1-12

Search

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

Ammonia mitigation campaign with smallholder farmers improves air quality while ensuring high cereal production

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Room-temperature direct synthesis of semi-conductive PbS nanocrystal inks for optoelectronic applications

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis

Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia/re-oxygenation-induced endothelial autophagy in vitro

Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a

STEM enables mapping of single-cell and spatial transcriptomics data with transfer learning

Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis

D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration

Genome assembly of Nannochloropsis oceanica provides evidence of host nucleus overthrow by the symbiont nucleus during speciation

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