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Signatures of mitonuclear coevolution in a warbler species complex

Little is known on how mitonuclear interactions influence genomic divergence among hybrid and parental lineages. A study of hybridizing wood warbler species complex finds a nuclear gene block with mitochondrial functions coevolves with mitochondrial genome, driven by climate-associated divergent selection underlying hybrid-parental population divergence.

Silu Wang
Madelyn J. Ore
Darren Irwin
ResearchOpen Access13 Jul 2021
Nature Communications

Volume: 12, P: 1-11
Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment

Risk prediction for prognosis in colorectal cancer is an important tool. Here, the authors utilise GWAS from 5 cohorts of colorectal cancer patients, and show a healthy lifestyle is associated with a 7.6% improvement in overall survival among patients with high pathologic and genetic risk.

Junyi Xin
Dongying Gu
Meilin Wang
ResearchOpen Access08 Apr 2024
Nature Communications

Volume: 15, P: 1-11
A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

A comprehensive transcriptomic survey of the pig could enable mechanistic understanding of tissue specialization and accelerate its use as a biomedical model. Here the authors characterize four distinct transcript types in 31 adult pig tissues to dissect their distinct structural and transcriptional features and uncover transcriptomic variability related to tissue physiology.

Long Jin
Qianzi Tang
Mingzhou Li
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-17
Alcohol consumption and risks of more than 200 diseases in Chinese men

Observational analyses from the China Kadoorie Biobank found that alcohol consumption was associated with higher risks of 61 diseases in Chinese men, with most of these associations confirmed by genetic analyses.

Pek Kei Im
Neil Wright
Xiaoyi Zhang
ResearchOpen Access08 Jun 2023
Nature Medicine

Volume: 29, P: 1476-1486
Costs and health benefits of the rural energy transition to carbon neutrality in China

Electric cooking and air-to-air heat pump adoption in China advances carbon neutrality and the rural energy transition, with the transformation costs offset by monetized health benefits in most provinces.

Teng Ma
Silu Zhang
Yang Xie
ResearchOpen Access29 Sept 2023
Nature Communications

Volume: 14, P: 1-11
Human papillomavirus integration perspective in small cell cervical carcinoma

Small cell cervical carcinoma (SCCC) is a rare but aggressive malignancy. Here, the authors report human papillomavirus features and genomic landscape in SCCC via high-throughput sequencing methods and identify MYC, SOX, NR4A, ANKRD and CEA family genes as HPV-integrated hotspots.

Xiaoli Wang
Wenlong Jia
Shuang Li
ResearchOpen Access10 Oct 2022
Nature Communications

Volume: 13, P: 1-10
Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses

Cryptosporidium parvum virus 1 is a virus harbored by the pathogenic protozoan Cryptosporidium parvum, and whose role in parasite biology and host interactions remains unclear. Here, Deng et al. demonstrate the impact this virus has on host response and infection outcome.

Silu Deng
Wei He
Xian-Ming Chen
ResearchOpen Access16 Mar 2023
Nature Communications

Volume: 14, P: 1-17
Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults

In a nested case-control study from the China Kadoorie Biobank, lowering blood low-density lipoprotein cholesterol levels confers lower risk for ischemic stroke but elevated risk for intracerebral hemorrhage, which was confirmed by genetic Mendelian randomization analyses.

Luanluan Sun
Robert Clarke
Zhe Qiu
Research11 Mar 2019
Nature Medicine

Volume: 25, P: 569-574
Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Matthew Chun
Robert Clarke
Libo Zhang
ResearchOpen Access02 Sept 2021
Scientific Reports

Volume: 11, P: 1-10
Identification of a BRAF/PA28γ/MEK1 signaling axis and its role in epithelial-mesenchymal transition in oral submucous fibrosis

Changqing Xie
Zaiye Li
Qianming Chen
ResearchOpen Access12 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-12
Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
ResearchOpen Access27 Mar 2020
Scientific Reports

Volume: 10, P: 1-11
Publisher Correction: Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Matthew Chun
Robert Clarke
Libo Zhang
Amendments and CorrectionsOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1
Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
Amendments and CorrectionsOpen Access12 May 2020
Scientific Reports

Volume: 10, P: 1-2

Search

Signatures of mitonuclear coevolution in a warbler species complex

Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

Alcohol consumption and risks of more than 200 diseases in Chinese men

Costs and health benefits of the rural energy transition to carbon neutrality in China

Human papillomavirus integration perspective in small cell cervical carcinoma

Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses

Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults

Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Identification of a BRAF/PA28γ/MEK1 signaling axis and its role in epithelial-mesenchymal transition in oral submucous fibrosis

Systemic inflammation is associated with incident stroke and heart disease in East Asians

Publisher Correction: Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians

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