G-CSF and GM-CSF are well-known regulators of hematopoiesis, but these cytokines also have proinflammatory activity and are expressed in the joints of patients with rheumatoid arthritis. Antagonism of G-CSF or GM-CSF might represent a novel, safe and effective way of treating this disease.
- Ann L. Cornish
- Ian K. Campbell
- Ian P. Wicks
