Nature Search

Publisher Correction: Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis

Camille Gelot
Marton Tibor Kovacs
Raphael Ceccaldi
Amendments and CorrectionsOpen Access25 Jan 2024
Nature

Volume: 626, P: E13
BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination

BRCA2 and its interactor HSF2BP are required for meiotic recombination. Here, the authors define the interaction structurally, revealing that a repeat in BRCA2 binds two HSF2BP units, increasing the affinity. This region is, however, not essential for mouse meiosis.

Rania Ghouil
Simona Miron
Alex N. Zelensky
ResearchOpen Access29 Jul 2021
Nature Communications

Volume: 12, P: 1-16
Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

The BRCA2 tumour suppressor protein is known to play an important role in homologous recombination. Here the authors reveal how the phosphorylation of BRCA2 by Polo-like kinase 1 (PLK1) contributes to the regulation of mitosis.

Åsa Ehlén
Charlotte Martin
Aura Carreira
ResearchOpen Access14 Apr 2020
Nature Communications

Volume: 11, P: 1-21
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Oestrogen negative breast cancer is associated with a poor prognosis. In this study, the authors perform a meta-analysis of 11 breast cancer genome-wide association studies and identify four new loci associated with oestrogen negative breast cancer risk. These findings may aid in stratifying patients in the clinic.

Fergus J. Couch
Karoline B. Kuchenbaecker
Antonis C. Antoniou
ResearchOpen Access27 Apr 2016
Nature Communications

Volume: 7, P: 1-13
Mechanism of MRX inhibition by Rif2 at telomeres

Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at telomeres.

Florian Roisné-Hamelin
Sabrina Pobiega
Stéphane Marcand
ResearchOpen Access12 May 2021
Nature Communications

Volume: 12, P: 1-16
Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis

In mitosis, genome integrity is maintained by DNA polymerase theta-dependent repair of DNA double-strand breaks, which is regulated by Polo-like kinase 1 activity.

Camille Gelot
Marton Tibor Kovacs
Raphael Ceccaldi
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: 415-422
Study of the relationship between applied transmembrane pressure and antimicrobial activity of lysozyme

Simona M. Miron
Ariane de Espindola
Arnaud Ponche
ResearchOpen Access08 Jun 2021
Scientific Reports

Volume: 11, P: 1-8
Age, comorbidity burden and late presentation are significant predictors of hospitalization length and acute respiratory failure in patients with influenza

Victor Daniel Miron
Oana Săndulescu
Anca Cristina Drăgănescu
ResearchOpen Access06 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
Refining skin lesions classification performance using geometric features of superpixels

Simona Moldovanu
Mihaela Miron
Luminita Moraru
ResearchOpen Access15 Jul 2023
Scientific Reports

Volume: 13, P: 1-14

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