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Showing 1–2 of 2 results
Advanced filters: Author: Sisira Kadambat Nair Clear advanced filters

  • Molecular heterogeneity of acute myeloid leukaemia (AML) across patients is a major challenge for prognosis and therapy. Here, the authors show that NPM1 mutated AML is a heterogeneous class, consisting of two subtypes which exhibit distinct molecular characteristics, differentiation state, patient survival and drug response.

    • Arvind Singh Mer
    • Emily M. Heath
    • Benjamin Haibe-Kains
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • It is no secret that a significant part of scientific research is difficult to reproduce. Here, the authors present a cloud-computing platform called ORCESTRA that facilitates reproducible processing of multimodal biomedical data using customizable pipelines and well-documented data objects.

    • Anthony Mammoliti
    • Petr Smirnov
    • Benjamin Haibe-Kains
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10