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Showing 1–2 of 2 results
Advanced filters: Author: Sjoerd Holwerda Clear advanced filters

  • Transcription factors are critical regulators of cell identity. Here, the authors use computational and functional genomic approaches to show an oncogenic role of PAX8 in renal cancer. Mechanistic dissection of PAX8 functions reveal its role in activating genes associated with metabolic pathways.

    • Melusine Bleu
    • Swann Gaulis
    • Giorgio G. Galli
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • A high-resolution 4C-seq protocol involving two restriction digests and a revised analysis pipeline allows robust detection of physical interactions between regulatory DNA elements.

    • Harmen J G van de Werken
    • Gilad Landan
    • Wouter de Laat
    Research
    Nature Methods
    Volume: 9, P: 969-972