Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Sofia Helfrich Clear advanced filters
  • Natural products have historically made a major contribution to pharmacotherapy, but also present challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization. This Review discusses recent technological developments — including improved analytical tools, genome mining and engineering strategies, and microbial culturing advances — that are enabling a revitalization of natural product-based drug discovery.

    • Atanas G. Atanasov
    • Sergey B. Zotchev
    • Claudiu T. Supuran
    Reviews
    Nature Reviews Drug Discovery
    Volume: 20, P: 200-216
  • Group 2 Innate lymphoid cells (ILC2) are a source of type 2 cytokines, such as interleukin-5 (IL-5). Here Troch, Jakob et al. show a non-redundant role of ILC2-derived IL-5 required for the development and function of a subset of murine B cells.

    • Karoline F. Troch
    • Manuel O. Jakob
    • Christoph S. N. Klose
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12
  • Specific deletion of group 2 innate lymphoid cells in mice shows these cells have roles in the recruitment of eosinophils and in mounting immune and epithelial type 2 responses.

    • Katja J. Jarick
    • Patrycja M. Topczewska
    • Christoph S. N. Klose
    Research
    Nature
    Volume: 611, P: 794-800